The Core of Neuromelanin
The core of neuromelanin is composed of pheomelanin and surrounded by eumelanin according to an article published in Biophysics and Computational Biology in 2006 entitled, “The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface.”
Consider the significance of this research cited in the abstract below:
“Neuromelanin (NM) isolated from the substantia nigra region of the human brain was studied by scanning probe and photoelectron emission microscopies. Atomic force microscopy reveals that NM granules are comprised of spherical structures with a diameter of ≈30 nm, similar to that observed for Sepia cuttlefish, bovine eye, and human eye and hair melanosomes. Photoelectron microscopy images were collected at specific wavelengths of UV light between 248 and 413 nm, using the spontaneous-emission output from the Duke OK-4 free electron laser. Analysis of the data establishes a threshold photoionization potential for NM of 4.5 ± 0.2 eV, which corresponds to an oxidation potential of −0.1 ± 0.2 V vs. the normal hydrogen electrode (NHE). The oxidation potential of NM is within experimental error of the oxidation potential measured for human eumelanosomes (−0.2 ± 0.2 V vs. NHE), despite the presence of a significant fraction of the red pigment, pheomelanin, which is characterized by a higher oxidation potential (+0.5 ± 0.2 V vs. NHE). Published kinetic studies on the early chemical steps of melanogenesis show that in the case of pigments containing a mixture of pheomelanin and eumelanin, of which NM is an example, pheomelanin formation occurs first with eumelanin formation predominantly occurring only after cysteine levels are depleted. Such a kinetic model would predict a structural motif with pheomelanin at the core and eumelanin at the surface, which is consistent with the measured surface oxidation potential of the ≈30-nm constituents of NM granules.”
Caucasians or Whites possess a predominance of pheomelanin throughout their organs and specifically in the largest of these. Blacks as seen in the skin enjoy the benefits of eumelanin due to cysteine levels not being depleted during genesis.
What is the significance of Black and White when the very melanin that confirms our humanity, neuromelanin, contains both pheomelanin at its base and eumelanin on its surface. This research was published in 2006 and yet what does it say about our humanity twenty years later? We are all Black and White, eumelanin and pheomelanin like our planet. Cold metal at the core and yet living color in its orbital bond with the sun. Profound. Were all of the subjects utilized in this research Caucasian or were the loci of Blacks utilized such that the neuromelanin was representative? If further studies find that the core of neuromelanin in Blacks contains on the core and surfacer, that finding would be remarkable. However, if all human neuromelanin from all races contains a pheomelanin core, the symmetry with others realms would also be an interesting consideration.
Consider that ferrous oxide or FeO composes the center of our planet, yet the surface engages that same oxygen with carbon, nitrogen, hydrogen and creates an organic reality that thrives in living color. From Feo to pheo. The earth and the melanin are synchonized. The core of the earch contains copper and Cu does somersaults around the C-H-O-N while appearing as melanin through out the organs whose origins are that neural crest. Even our human bodies, at their foundation are bones, hard like copper, iron, and off-white like pheo melanin surrounded by flesh, organic vibrant tissue that pulses and interacts. The Divine Creatress has a magical sense of vision and humor. Truly.